- Zac Efron - actor
- Zac Hanson - musician, Hanson
- Zac Rinaldo - athlete, hockey player, Philadelphia Flyers
- Zach Braff - actor
- Zach Parise - athlete, hockey player, New Jersey Devils
- Zach Roerig - actor
- Zachary Galifianakis - actor
- Zachary Levi - actor
- Zachary Quinto - actor
- Zak Bagans - television personality, Ghost Adventures
- Zoe Kravitz - actress, musician
- Zoe Saldana - actress
- Zooey Deschanel - actress